Background: Breast Cancer is a health problem in Cuba because of high incidence and mortality rates. It is the most common cause of cancer among women excluding skin cancer. It is also the second cause of cancer death in women. Objective:  to describe the burden of breast cancer, focusing of the geographical and temporal variations in incidence and mortality.
Methods: Based on the data provided by the National Cancer Registry (NCR) for the period 2010-2019, age specific rates and world adjusted rates (ASWR) were calculate using the direct method. The distribution in percentile of ASWR by province was used to
show the geographical distribution. A trend analysis of incidence and mortality since 2000 was performed using jointpoint regression.
Results: An annual average of 2511 new cases were diagnosed, with a ASWR of 42 cases per 100 000 inhabitants. There is an increasing trend for incidence (p < 0.05) with a 2% annual average change (95% Confidence Interval, 1.5-2.7). The highest risk group was that of 60 years or older, which represents 52% of all the diagnosed cases, with around 2109 new cases and a rate of 164.5 for every 100 000 women. Most of the Breast cancer cases are diagnosed in localized stage. Nevertheless, no change is observed in the proportion of cases diagnosed at advanced stage (25%). but difference in the stage distribution by province was observed. A decreasing mortality trends is observed in the last years as well as improve in overall survival. This could be associated with the introduction of guideline for diagnosis and treatment in whole country.
Conclusions: Actions for improve outcome in breast cancer have shown promissory results. Actions based in secondary prevention are doing taken into account geographical incidence.