BACKGROUND
Cancer represents the second highest cause of mortality and morbidity in Europe, with nearly half of cases attributable to modifiable behavioural risk factors, including tobacco use, alcohol, physical inactivity, unhealthy diet, and ultraviolet exposure. These behavioural risks often co-occur, and the disease burdens are disproportionately concentrated among disadvantaged populations, migrants, and people living with low socioeconomic status (SES), facing intersecting social and structural barriers to prevention and treatment. Practical, tailored multi-factor prevention strategies are required to reduce this avoidable cancer.
 
OBJECTIVES
PEACHD (Piloting European Action on Cancer Health Determinants - ref:101129260), an EU-funded initiative, aims to reduce cancer and noncommunicable disease risk among displaced and low-SES populations by:
- developing a scalable intervention, adaptable to diverse sociocultural contexts;
- strengthening capacity across health and community systems through;
- and improving health literacy and reducing behavioural risk factors.

METHODS
PEACHD builds on the WHO BRIEF Manual delivering Screening and Brief Motivational Interventions (SBMI), piloted in three distinct healthcare/social settings in Poland, Czechia, and Spain. 
PEACHD trains diverse delivery agents - primary care professionals serving disadvantaged neighbourhoods (Catalonia), community staff and professionals in Ukrainian refugees’ reception centres (Poland), displaced health professionals and social workers serving diaspora (Czechia) - in evidence-based behavioural screening, tailored guidance tools and motivational skills to support holistic positive lifestyle change in service users.
Trans-cultural adaptation and capacity building underpin the project. Interventions are delivered in variable formats, including individual/group sessions, and digital, allowing adaptation to local infrastructure and participant needs. Materials and training are linguistically and culturally tailored for differing risk profiles and social contexts. Structured multi-modal training, health-promoting guidance materials, and digital tools to support consistent messaging and sustainability.
Evaluation is guided by the RE-AIM framework assessing core implementation indicators relating to training, satisfaction and capacity of providers; and adaptation of intervention tools; and intervention delivery.
 
RESULTS
PEACHD has been successfully rolled-out in 41 sites across the three pilot settings; training 503 professionals serving disadvantaged populations (with training still ongoing). Early implementation data indicates feasibility for multi-risk SBMI delivered by non-traditional agents in diverse settings. Varied duration options and group/individual formats have enabled agents to reach populations with varying levels of service contact and health literacy.
To date 828 service users in Czechia and Poland have received the intervention (558 in-person, 270 online), with Catalan data still pending, indicating that PEACHD strengthens provider competencies in motivational skills and culturally responsive prevention, while project materials support participant engagement in cancer prevention. Trans-cultural evaluation data are currently being gathered and more complete findings expected for the conference.
 
CONCLUSIONS / IMPLICATIONS
PEACHD illustrates the potential of flexible, multi-risk-factor behavioural interventions to deliver cancer prevention among displaced and low-SES populations. By mobilising diverse delivery agents, offering variable intervention formats, and prioritising trans-cultural adaptation and health literacy, the programme addresses individual behaviours and systemic barriers to prevention. PEACHD provides a scalable and transferable approach aligned with the EU Beating Cancer Plan and broader cancer and NCD prevention strategies, with implications for reducing avoidable cancer burden and health inequalities internationally.