Theme: Translating research into public health actions: implementation research, digital health
 
Integrating smoking cessation via mobile application with low-dose CT-screening for lung cancer – a randomized pilot study
 
Sarkeala T1, Heinävaara S1, Lamminmäki M1, Iivanainen S2,3, Koivunen J2,3
 
1 Finnish Cancer Registry, Helsinki, Finland
2 Oulu University, Oulu, Finland
3 Oulu University Hospital, Oulu, Finland
 
Background
Low-dose computed tomography (LDCT) screening has demonstrated efficacy in reducing lung cancer mortality among individuals with a history of heavy smoking. Evidence further suggests that integrating smoking cessation interventions within screening programs can amplify this mortality benefit. Despite these findings, LDCT screening is currently implemented only in a limited number of European countries, and few have incorporated smoking cessation strategies into their protocols.
 
Objectives
To evaluate the feasibility and effectiveness of integrating smoking cessation interventions with LDCT lung cancer screening in a randomized trial setting in Finland. Specific aims include assessing the efficiency of different cessation methods, screening performance, and the impact of screening on stage-specific lung cancer incidence. The study is conducted within the EUCanScreen Joint Action framework.
 
Methods
The trial targets 1200 current smokers aged 50–74 years with a smoking history of >15 cigarettes/day for >25 years or >10 cigarettes/day for >30 years. Participants are randomized (1:1:2) into two intervention groups and one control group. Intervention groups receive LDCT screening at baseline and at year 2, combined with either smoking cessation counseling via a mobile phone application or standard written materials. The control group receives active counselling through the mobile phone application only. Recruitment will be carried out through multiple channels, including local newspapers and social media, as no national smoker registry exists. Data will be collected at the individual level in the Finnish Cancer Registry and linked to other healthcare registers.
 
Results
Preliminary findings will be presented.
 
Implications
Insights into the challenges and opportunities of integrating smoking cessation with LDCT screening will inform best practices to reduce lung cancer mortality across Europe.