IARC 60th Anniversary - 19-21 May 2026
Session : Classifying Cancer, Changing Lives
The WHO Classification of Tumours Evidence Explorer: a WCT EVI MAP software tool
CIERCO JIMENEZ R. 1
1 International Agency for Research on Cancer (IARC), World Health Organization, 25 Avenue Tony Garnier, CS 90627, 69366 LYON CEDEX 07, France, Lyon, France
Background
Evidence-based practice has substantially advanced cancer pathology, research, and tumour classification. However, systematically identifying high-quality evidence and clearly characterizing evidence gaps remains a challenge for both researchers and clinicians.
Objective
To develop a software tool that allows to explore evidence gap maps (EGMs) of scientific literature to support evidence-based decision-making in tumour classification and facilitate identification of knowledge gaps and pockets of low-level evidence to inform future research priorities and health policies in the field.
Methods
We developed an intuitive web application that integrates EGMs in a searchable database of scientific evidence related to tumour classification. The application is built entirely on open-source technologies. The user interface was implemented using R Shiny (R v4.3.3; Shiny v1.8.1.1), while the backend database prototype uses MariaDB (v10.4.32), a MySQL-compatible relational database. Both components were optimized to support dynamic querying and responsive interaction, enabling efficient exploration of complex evidence structures.
Results
The application consists of three main components to enable the end-user to perform a focused exploration of specific areas within the retrieved evidence: