Abstract
Background: Cervical cancer remains a major public health concern globally. It’s the fourth cause of cancer deaths among women worldwide. In 2020, global incidence of cervical cancer was estimated to be 604000 with a standardized mortality rate of 341000. In Tanzania, cancer of cervix is the most common female cancer and a leading cancer-related deaths. Majority of data demonstrating survival rate of cervical cancer originate from high and middle income countries with contributions from  low income countries including Tanzania is relatively scarce. Describing factors associated with survival is critical in attempt to inform strategies to improve outcome of women with cervical cancer.
 
Objective: To determine the three years overall survival rate and associated factors among women with invasive cervical cancer attended at Ocean Road Cancer Institute (ORCI) from 2018 to 2020.
 
Methods: A retrospective cohort study was conducted at ORCI by using cancer registry database. The study included 256 women diagnosed with cervical cancer from 2018 to 2020. Survival analysis was estimated by using Kaplan-Meir analysis, Cox regression hazard proportion and log-rank test and p-value of <0.05 was considered statistically significant. Stata version 17 was used for analysis.
 
Results:  Among 256 women with cervical cancer, the survival rate in 1,2 and 3 years were 83.6%, 77.0%, and 72.7% respectively. Survival rate was statistically significantly associated with FIGO stage during diagnosis and hemoglobin level. Those who received concurrent chemoradiotherapy had high survival rate compared to those who received radiotherapy or chemotherapy only, and it was statistically significant with P< 0.001.
 
Conclusion: The study found an overall survival rate of 72.7% over three years. Factors associated with survival rate were early FIGO stage at diagnosis, normal hemoglobin level at diagnosis, and the use of concurrent chemoradiotherapy. Proper staging, good patient preparation and good choice of treatment improves survival. With availability of advance treatment options in the country survival rate of women is promising.