Background:

Despite major advances in cancer research, rural populations in Low- and Middle-Income Countries (LMICs) continue to face critical barriers in accessing timely diagnosis, treatment, and palliative care. In India’s rural districts, late-stage presentation, poor health literacy, and financial toxicity are major contributors to poor outcomes. Civil society organizations and patient advocates can bridge the gap between research and real-world implementation by fostering local engagement, home-based interventions, and health system linkages.

Objectives:

This study aimed to (1) evaluate the impact of community-led oncology social work and home-based care models on improving access, adherence, and quality of life among rural cancer patients; (2) assess the role of patient advocacy in shaping local cancer policy and awareness; and (3) identify scalable strategies for integrating civil society-driven cancer care within LMIC public health frameworks.

Methods:

A mixed-method community-based participatory approach was used in two rural blocks of East Medinipur District, West Bengal, India. Data were collected from 212 patients enrolled in the Narikeldaha PRAYAS Home Care Programme between 2021–2024. Quantitative indicators included access to chemotherapy, pain management, and follow-up compliance. Qualitative interviews explored barriers, advocacy outcomes, and psychosocial impacts. Partnerships were established between MAS Clinic & Hospital (Tamluk), community volunteers, and oncology professionals to ensure continuity of care and patient education.

Results:

Over three years, 68% of patients reported improved treatment adherence, and 74% experienced better pain and symptom control through structured home visits and counseling. Community advocacy led to the establishment of two rural cancer awareness hubs and a local chemotherapy access program, reducing patient travel burden by 60%. Partnerships with oncology institutions and international cancer networks enabled knowledge transfer, digital health adaptation, and local capacity-building.

Conclusions / Implications:

Grassroots oncology care and patient advocacy are powerful public health tools in LMICs, translating research evidence into equitable cancer control. Integrating trained oncology social workers and community advocates within national cancer strategies can significantly improve outcomes, reduce disparities, and advance planetary health goals through sustainable, low-cost interventions. The Narikeldaha PRAYAS model demonstrates that global cancer research can achieve true impact when translated into rural community action—empowering patients, strengthening systems, and transforming policy.